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Welch

Technology & Capabilities

Welch Materials, Inc. is a global chromatography innovator with headquarters in Shanghai and subsidiaries in the USA, India, and Canada. Since 2003, Welch has specialized in HPLC & GC columns, chromatographic packing materials, sample prep, protein purification, and laboratory consumables. With ISO 9001:2015 certification, Welch delivers quality, reproducibility, and trust for pharma, biotech, food safety, and environmental labs worldwide

Product / Instrument Ranges

Product / Series Description / Features
Diamond DLC Series Next-gen performance: Diamond-coated column tubes minimize metal ion interference and boost sensitivity. Applications: Proteins, oligonucleotides, biomolecules, and metal-sensitive small molecules. Key Features: Mass spec peak signals up to 10× higher than stainless-steel columns.
Ghost-Buster™ Columns Removes low-polarity impurities that cause ghost peaks during gradient elution. Extends column/system lifetime by preventing contamination. Available in Standard and Ghost-Buster II versions with enhanced baseline stability.
Ultisil® Series Classic high-purity silica columns (USP-listed). Key features: • Ultra-pure silica (>99.999%) • Excellent peak symmetry (TF 0.95–1.05) • Broad pH stability (2.0–8.0) • High batch-to-batch reproducibility Applications: APIs, small molecules, complex mixtures.
Xtimate® Series Hybrid & polymer-based columns for challenging separations (peptides, proteins, sugars). Includes SEC, Bio SEC & polymer phases. High mechanical strength suitable for prep-scale purification.
Welchrom® Series Reliable C18, C8 & specialty phase columns for routine HPLC analysis. Strong reproducibility and consistent performance.
Boltimate® Core-shell technology for faster run times, higher efficiency, and lower backpressure. Ideal for UHPLC & high-throughput workflows.
Blossmate® Series Specialized columns for complex bioanalytical applications. Available in C18, SAX, Phenyl, and Polar Propylamide phases.
UHPLC Columns UHPLC versions of Ultisil® & Xtimate® available. Sub-2 μm particles for high-resolution & rapid pharma/bio analyses.

Why Choose Welch Columns?

  • Wide phase chemistry coverage (C18, C8, Phenyl, CN, HILIC, SEC, PFP, Mixed-Mode, Chiral).
  • Proven equivalency to leading global brands (Agilent, Waters, Phenomenex).
  •  Excellent balance of performance & cost-efficiency.
  •  Local presence in India with strong technical & after-sales support.

Industries We Serve

  • Pharmaceuticals & Biopharma – peptide/oligo purification, impurity profiling, nitrosamine analysis.
  • Food Safety – detection of mycotoxins, preservatives, additives.
  • Environmental Monitoring – pesticide residues, pollutants.
  • Academic & Research Labs – method development & training

Product Specification

Diamond DLC Series HPLC Columns

Overview

Next-generation columns with Diamond-Like Carbon (DLC) coating. Minimize metal ion interference, reduce adsorption, and deliver ultra-sensitive detection.

Application

Proteins, nucleic acids, oligonucleotides, peptides, and metal-sensitive small molecules.

Key Benefits

  • Up to 10× stronger MS peak signals vs stainless steel columns
  • Extended column lifespan
  • Excellent for UHPLC & LC-MS analysis

Specifications

  • Particle Size: 1.8 µm – 5 µm
  • Formats: C18, Bio SEC-300, Polar RP, Diol, AQ-C18, etc.
  • pH Range: 2.0 – 8.0

Compatible Modes: SEC, Reversed Phase, Bio-Separations

Ghost-Buster™ Columns

Overview

Specialized impurity-removal columns that eliminate ghost peaks caused by mobile phase contamination. Installed between mixer and injector to protect both system and analytical columns.

Application

Gradient methods, long runs, mobile phases prone to ghost peaks

Key Benefits

  • Removes non-polar & weakly polar impurities
  • Extends column/system lifetime
  • Stable baseline with Ghost-Buster II (latest upgrade

Specifications

  • Sizes: 2.1–7.8 mm ID × 30–50 mm
  • Pressure: 40–100 MPa
  • Formats: Ghost-Buster I, Ghost-Buster II, High-Pressure variants

Ultisil® Series HPLC Columns

Overview

Flagship analytical columns using ultra-pure fully porous silica (>99.999%). Known for reproducibility, stability, and versatility

Application

Small molecules, APIs, method development, impurity profiling.

Key Benefits

  • Particle Sizes: 3 µm, 5 µm, 10 µm
  • Surface Area: 320 m²/g (120 Å), 90 m²/g (300 Å)
  • Carbon Load: 17% (120 Å), 8% (300 Å)
  • USP Code: L1
  • Endcapped: Yes

Specifications

  • Particle Sizes: 3 µm, 5 µm, 10 µm
  • Surface Area: 320 m²/g (120 Å), 90 m²/g (300 Å)
  • Carbon Load: 17% (120 Å), 8% (300 Å)
  • USP Code: L1
  • Endcapped: Yes

Other Phases: C8, Phenyl, C4, CN, NH2, SAX, SCX, C30, Mixed-Mode, Chiral, Specialized (PAH, Amino Acid, OAA, etc.).

Xtimate® Series HPLC Columns

Overview

Hybrid and polymer-based silica columns for complex separations. Excellent chemical stability and selectivity.

Application

Peptides, proteins, sugars, polymers, macromolecules.

Key Benefits

  • SEC & Bio SEC for large biomolecules
  • Polymer phases for sugar analysis (Ca²⁺, H⁺)

Specifications

  • Particle Size: 3 µm – 10 µm
  • Pore Sizes: 120 Å, 300 Å
  • Available Phases: C18, C8, C4, Phenyl-Hexyl, CN, Polar-RP, NH2, SEC, Bio-SEC

Boltimate® Core-Shell Columns

Overview

High-efficiency core-shell particle technology for faster analysis and lower backpressure.

Application

UHPLC/fast LC methods, high-throughput pharma labs.

Key Benefits

  • Narrow peak widths → higher sensitivity
  • Reduced solvent consumption
  • Faster run times without sacrificing resolution

Specifications

  • Particle Size: 2.6 µm (core-shell)
  • Phases: C18, C8, Phenyl, Phenyl-Hexyl, PFP, HILIC, LP-C18
  • USP Codes: L1, L11, L7, L26

Welchrom® Series

Overview

Reliable and affordable columns for routine analysis.

Application

Pharmaceutical QC, food testing, environmental analysis.

Phases Available

 C18, C8, Vantage C18 (high-endurance).

 Blossmate® Series

Overview

Tailored for complex bioanalytical needs.

Phases

C18, SAX, Phenyl, Polar-Propylamide, PSV C18 (for stability testing).food testing, environmental analysis.

UHPLC Columns

Overview
Sub-2 µm particle columns delivering ultra-fast, high-resolution separation.

Applications

Critical pharmaceutical and biomolecule analysis.

Available Families

 Ultisil UHPLC (C18, C8, Phenyl, PFP, HILIC) and Xtimate UHPLC (C18, Phenyl-Hexyl).

Your Trusted Partener in advanced diagnostic solution for ever healthcare need.

Contact us today for a free Consulation for more information.

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