Here’s the deal. We’re all about helping biologics and gene therapy researchers break free from tools that just don’t cut it. Unleashing problem-tackling solutions that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it.
unty is the fastest and highest throughput protein stability characterization tool on the planet. Period. With unrivaled fluorescence, Static Light Scattering (SLS) and Dynamic Light Scattering (DLS) skills, Aunty blasts through thermal melting and aggregation experiments — reading an entire 96-well plate of samples every minute of a thermal ramp. Sift through piles of candidates, conditions, or formulations, with as many replicates as you want. Aunty cranks out plates of results with unprecedented data resolution, so you can find your winners at breakneck speed.
More Details: Aunty – High-Throughput Protein Stability Characterization | Unchained Labs
Stunner is the only system that pulls together UV/Vis concentration and dynamic light scattering on the same 2 μL sample. Nail down your lipid nanoparticle quality by knocking particle concentration, size, mass, detection of aggregates and total RNA off your list in one shot. Rack up protein concentration, sizing, and aggregate detection, all at once. Dig in to your AAV or AdV to get the total capsid titer and empty/full ratio. Without skipping a beat, you’ll know if your LNPs, proteins or viral vectors are good to go.
More Details : Stunner -The Ultimate Quantification & Sizing Tool | Unchained
Lunatic, our next-gen UV/Vis spectrophotometer, makes batch quantification of protein, DNA and RNA a no-brainer. All you need is 2 μL and 10 minutes to measure up to 96 samples. Run them straight-up, even at high concentrations, without ever diluting.Lunatic gets biologics and genomics UV/Vis quantification on the money every time. Just drop, load and read.
More Details : Lunatic – UV/Vis Spectrophotometer | Unchained Labs
Finding the perfect LNP formulation can feel like it drags on forever. You need to figure out the best lipid mixture, the right lipid to payload ratio and the optimal flow rates to mix it all together. Worst of all, it’s usually done one experiment at a time. Sunscreen totally flips the script by creating 96 unique, small volume LNP formulations in less than 6 hours – so you can explore more formulations in a single day than you ever though.
More Details : Sunscreen – LNP Formulation Screening | Unchained
Once you’ve found a rock-solid formulation, Sunshine helps you tune in your LNP’s size and design the perfect process to scale them up. Scout ideal flow rates, explore different mixing options, then dial in the right dilution factor to keep them stable. When you’ve got everything just right, Sunshine can shift into continuous mode, making tens of liters in a day. Get process development and scale-up on one platform — who would have figured?
More Details : Sunscreen – LNP Formulation Screening | Unchained
Transferring your LNPs to GMP can be a costly, messy process. It usually means switching equipment, using a different flow path and mixer — basically a painfulre-development and re-validation of all your hard work. Sunbather makes the move to GMP a walk in the park with the documentation, replaceable flow path and easy transfer built right in. It uses the same mixing process and protocol as its Sunny Suite family members Sunscreen and Sunshine, so you can take your dialed in formulation into GMP without all the fuss.
More Details : Sunbather – GMP-ready LNP Production | Unchained Labs
Honeybun is the only rapid viscometer and rheometer that pours out data as fast as you can handle it. Whether you’ve got one sample or ten, Honeybun sips microliters of each sample through a microfluidic channel to get a read on viscosities from 0.5 –150 cP in minutes – with zero sample prep or clean-up. Ditch old school, one-at-a-time techniques that use too much sample and level up to the quickest, low-volume viscosity measurements out there.
More Details : Honeybun – The Ultimate Small Volume Viscometer | Unchained Labs
Leprechaun is the only system that hunts down titer and structure for viruses and exosomes without worrying about sample purity. Triple-check lentivirus particles to be sure they are the right size, have the right structure and contain RNA in both crude and pure samples. Uncover exosome concentration and phenotype in everything from cell culture to biofluids. Make your own luck and follow Leprechaun straight to the viral titer or exosome concentration you’ve been looking for, without the noise from trickster particles throwing you off the trail.
More Details : Leprechaun-Your Lentivirus Characterization Tool | Unchained Labs
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