WelPacker Dynamic Axial Compression (DAC) Columns
High-Performance Packing • Industrial Durability • Scalable for Every Purification Need
Welch DAC Columns are engineered for high-efficiency packing and large-scale chromatographic purification. Using advanced Dynamic Axial Compression (DAC) technology, these columns maintain constant, uniform compression on the packing bed—improving stability, extending media lifetime, and delivering superior reproducibility from batch to batch.
Whether purifying peptides, oligonucleotides, biopharmaceuticals, natural products, or chemical intermediates, Welch DAC Columns provide reliable, scalable solutions from 50 mm to 2000 mm internal diameter.
Key Technologies & Features
Uniform Packing & High Efficiency
Consistent axial pressure ensures a stable and uniform packing bed, delivering sharper peaks and reproducible purification profiles.
Scalable for All Production Needs
Available in a full range of diameters from small pilot-scale (50 mm) to industrial production-scale (2000 mm).
Superior Mechanical Precision
Polished internal surfaces (≤ 0.2 μm Ra) improve flow dynamics and reduce carryover.
Compatible with All Media Types
Silica, polymeric, HILIC, C18, ion-exchange, mixed-mode, and custom packing material
Safe & Reliable Operation
Overpressure protection and robust design make it suitable for long-term operation in GMP environments.
Easy Maintenance & Replicable Packing
Quick disassembly structure reduces downtime and simplifies re-packing.